Prayer Against the Spirit of Python

The first time I heard about the spirit of Python, I was in a spiritual warfare prayer group, and someone shared how they felt spiritually suffocated—like something was slowly draining their energy, cutting off their ability to pray, and causing stagnation in their life. It felt like an invisible force was constricting them spiritually. If you’ve ever felt this way—suffocated, overwhelmed, or as if your spiritual life is under attack—you may be dealing with the spirit of Python.

The spirit of Python is a demonic force referenced in Acts 16:16, where the apostle Paul encounters a slave girl with a spirit of divination, often associated with Python. This spirit operates by suffocating your spiritual life, constricting your prayer, and draining your spiritual energy, much like a physical python would constrict and suffocate its prey. It brings stagnation, prevents spiritual growth, and creates a sense of spiritual heaviness and weariness.

If you suspect that you are under attack from the spirit of Python, prayer is your most powerful weapon. Below are warfare prayers designed to break the stronghold of this spirit and restore your spiritual vitality.


Signs of the Spirit of Python

Before diving into prayers, it’s important to understand how the spirit of Python manifests. Here are some common signs:

  • Spiritual Stagnation: Feeling stuck in your prayer life or unable to make progress in your relationship with God.
  • Oppression or Heaviness: A sense of overwhelming heaviness or weariness, especially when trying to pray or worship.
  • Difficulty Breathing: In severe cases, people have reported feeling as if they are physically suffocating or having difficulty breathing.
  • Lack of Spiritual Desire: A loss of desire to read the Bible, pray, or engage in spiritual disciplines.
  • Financial or Personal Stagnation: This spirit doesn’t just attack your spiritual life—it can also bring stagnation in areas such as finances, career, or relationships.

Steps to Break Free from the Spirit of Python

1. Repentance and Confession

The first step in dealing with any demonic spirit is repentance. Sin can open doors for spiritual attacks, including the spirit of Python. Repent of any known sins, especially those involving divination, witchcraft, or occult practices, which may have given this spirit access to your life.

“Heavenly Father, I come before You in the name of Jesus, repenting of any sin that has opened the door to the spirit of Python. I renounce every connection to divination, witchcraft, or occult practices, whether knowingly or unknowingly. Cleanse me with the blood of Jesus and close every demonic door in my life. I surrender completely to You, Lord, and ask for Your protection and deliverance.”


2. Break the Python’s Hold Through Fasting and Prayer

Fasting is a powerful tool in breaking demonic strongholds, and the spirit of Python is no exception. Engage in a period of fasting—it could be from 6 a.m. to 6 p.m. or even a longer period—combined with targeted prayers.

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3. Warfare Prayer to Break the Spirit of Python

Here is a structured warfare prayer to use against the spirit of Python. This prayer focuses on binding and casting out the spirit, as well as declaring your freedom in Christ.


Prayer Against the Spirit of Python

  1. Opening Praise: Start with praise and worship, acknowledging God’s power and sovereignty over all things.
  2. Repentance and Renunciation:

    “Father, I come before You with a heart of repentance. I confess and renounce any sin or act of rebellion that may have allowed the spirit of Python access into my life. I reject all forms of divination, witchcraft, and occult activities that may have been practiced by me or my ancestors. In the name of Jesus, I break every legal right the spirit of Python has over me and my household. I declare myself free from its grip in Jesus’ name.”

  3. Binding and Casting Out the Spirit of Python:

    “In the name of Jesus, I bind every spirit of Python operating in my life. You constricting spirit, I command you to release your hold over me right now! I cast you out by the authority of Jesus Christ. Every spirit that is suffocating my prayer life, draining my energy, and blocking my spiritual growth, be destroyed by the fire of the Holy Ghost!”

  4. Breaking Spiritual Stagnation:

    “Every stagnation in my spiritual life, every attack on my finances, relationships, or health caused by the spirit of Python, be broken right now in Jesus’ name! I declare that the power of God is breaking every yoke of bondage. I will move forward in Jesus’ name, and every area of my life that has been hindered is now free!”

  5. Declaring Freedom:

    “I declare that I am free from every entanglement of the spirit of Python. The Lord has given me victory, and no weapon formed against me will prosper. I declare that my prayer life is revived, my spirit is refreshed, and my connection to God is restored, in the mighty name of Jesus!”

  6. Sealing the Prayer:

    “I seal my deliverance with the blood of Jesus. I declare that every attempt of the spirit of Python to return is null and void. I am covered by the blood of the Lamb, and I walk in victory and freedom. In Jesus’ name, Amen!”


4. Confessing Scripture Over Your Life

The Word of God is a powerful weapon in spiritual warfare. When battling the spirit of Python, declare these scriptures over your life:

  • Isaiah 54:17 – “No weapon formed against you shall prosper, and every tongue which rises against you in judgment you shall condemn.”
  • Luke 10:19 – “Behold, I give you the authority to trample on serpents and scorpions, and over all the power of the enemy, and nothing shall by any means hurt you.”
  • Matthew 18:18 – “Truly I tell you, whatever you bind on earth will be bound in heaven, and whatever you loose on earth will be loosed in heaven.”
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5. Pray for Spiritual Revival and Refreshing

After breaking free from the spirit of Python, pray for a fresh outpouring of the Holy Spirit to renew and revive your spiritual life.

“Father, I ask for a fresh outpouring of Your Spirit in my life. Renew my desire to pray, read Your Word, and seek Your face. Restore everything the enemy has tried to steal from me. Let the breath of the Holy Spirit fill me and refresh my soul, bringing me new life, strength, and purpose. In Jesus’ name, Amen.”


6. Close All Spiritual Doors

Ensure that the spirit of Python has no way back into your life by closing all spiritual doors. This includes staying away from anything that could open you up to spiritual attacks, like:

  • Sinful habits (especially ones connected to pride, rebellion, or divination)
  • Negative associations or relationships that pull you away from God
  • Occult practices or anything that links to witchcraft or new-age practices
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Pray this:

“Lord, I ask You to close every door that I may have opened to the enemy. Help me to live in purity and righteousness, walking in obedience to Your Word. Keep me under the protection of Your wings, and help me discern anything that could allow this spirit to re-enter my life. In Jesus’ name, Amen.”


Final Thoughts

The spirit of Python is a formidable enemy, but through targeted, faith-filled prayers, repentance, and reliance on God’s power, you can break its hold. Spiritual warfare is not passive—it requires persistence and a reliance on God’s Word and the Holy Spirit. Stay alert, stay in prayer, and remember that God has given you authority over all the power of the enemy.

You are more than a conqueror through Christ, and you can walk in freedom, spiritual vitality, and renewed strength!

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